Case 236: Middle Interhemispheric Variant of Holoprosencephaly
نویسندگان
چکیده
منابع مشابه
The middle interhemispheric variant of holoprosencephaly.
BACKGROUND AND PURPOSE The middle interhemispheric variant of holoprosencephaly (MIH) is a rare malformation in which the cerebral hemispheres fail to divide in the posterior frontal and parietal regions. We herein describe the structural abnormalities of the brain in a large group of patients with MIH, compare these features with those of classic holoprosencephaly (HPE), and propose a developm...
متن کاملPrenatal MR findings of the middle interhemispheric variant of holoprosencephaly.
We report a case of the middle interhemispheric variant of holoprosencephaly (MIH) with noncleavage of the posterior portion of the frontal lobes and the parietal regions in a fetus at 22 weeks' gestation. To our knowledge, this is the first case of the rare MIH variant to be diagnosed in utero by use of ultrafast MR imaging and one of the few such reports to document gross and microscopic path...
متن کاملMiddle interhemispheric variant of holoprosencephaly associated with diffuse polymicrogyria.
An 11-month-old boy was discovered to have a cleft palate, club foot, hypospadias, and myoclonic seizures. No in utero exposure to teratogens was identified. Brain MR imaging revealed a middle interhemispheric fusion variant of holoprosencephaly, diffuse polymicrogyria, and a hypoplastic brain stem; this was a distinctly unusual association of findings. We hypothesize that an unknown genetic fa...
متن کاملMiddle interhemispheric holoprosencephaly with subdural hematoma.
Background: A 4-month-old boy with prenatal sonography findings consistent with corpus callosum agenesis and ventriculomegaly presented. Patient was born at 37-weeks from 18-yearold woman, gravida 1 para 1. There was no history of teratogen exposure in utero such as radiation, alcohol, drug or postnatal trauma. There was no family history of brain malformations nor chromosomal abnormalities. Cl...
متن کاملMiddle Interhemispheric Fusion: An Unusual Variant
PURPOSE: To describe the imaging features of a brain anomaly found on studies of three patients, and to speculate on the embryologic basis leading to the development of this abnormality. PATIENTS AND METHODS: Clinical records (three patients) , MR scans (two patients). and CT scans (two patients) of three patients with fusion of the middle portions of the cerebral hemispheres in the presence of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Radiology
سال: 2016
ISSN: 0033-8419,1527-1315
DOI: 10.1148/radiol.2016150503